Tirasemtiv (CK-2017357)

Tirasemtiv (formerly known as CK-2017357), a fast skeletal muscle troponin activator, which is being developed as a potential treatment for diseases and conditions associated with aging, muscle weakness and wasting or neuromuscular dysfunction. Tirasemtiv selectively activates the fast skeletal muscle troponin complex and increases its sensitivity to calcium, resulting in increased skeletal muscle force and slowing of time to muscle fatigue.

Development Status of Tirasemtiv

Amyotrophic Lateral Sclerosis Phase III Clinical Trial Details

Amyotrophic Lateral Sclerosis Phase II Clinical Trials Details

Myasthenia Gravis Phase IIa Clinical Trial (CY 4023) - Complete Details

Claudication Phase IIa Clinical Trial (CY 4022) - Complete Details

Phase I Clinical Trials Details