Significant advances in cancer therapy are closely associated with the identification of drugs with novel mechanisms of action. Cytokinetics’ oncology programs are focused on the discovery and development of small molecule therapeutics targeting cytoskeletal proteins. The cytoskeleton is involved in multiple biological processes with direct relevance to oncology, including mitosis, cell division, motility and cell adhesion. Our activities span several different approaches with each of these programs being driven by our unique focus on the genomics, biochemistry and cell biology of the cytoskeleton, and fueled by medicinal chemistry, pharmacology and novel technologies in high throughput screening. These highly collaborative efforts represent the forefront of this new and exciting drug discovery arena.
